Tomatoes May Be Winning Over Cancer


A nutrient in cooked tomatoes has been shown in laboratory studies to slow the growth of - and even kill - prostate cancer cells, scientists said today.

Dr Mridula Chopra and colleagues at the University of Portsmouth tested the effect of the nutrient lycopene on the simple mechanism through which cancer cells hijack a body's healthy blood supply to grow and spread.

Lycopene Molecule

They found that lycopene, which is what gives tomatoes their red colour, intercepts cancer's ability to make the connections it needs to attach to a healthy blood supply.
The researchers, from the university's School of Pharmacy and Biomedical Sciences, are now calling for tests to check if the same reaction occurs in the human body.

Director of the research Dr Chopra said: ''This simple chemical reaction was shown to occur at lycopene concentrations that can easily be achieved by eating processed tomatoes.''

Lycopene is present in all red fruits and vegetables, but its concentrations are highest in tomatoes and it becomes more readily available and biologically active when it comes from processed tomatoes with a small amount of cooking oil added.

Dr Chopra said: ''I stress that our tests were done in test tubes in a laboratory and more testing needs to be carried out to confirm our findings, but the laboratory evidence we have found is clear - it is possible to intercept the simple mechanism some cancer cells use to grow at concentrations that can be achieved by eating sufficient cooked tomatoes.''

Prostate Cancer Cells

In the laboratory experiments, lycopene was shown to disrupt the all important cancer cell linking process, without which cancer cells cannot grow. The researchers explained that all cancer cells use a similar mechanism (angiogenesis) to ''feed'' upon a healthy blood supply.


They said there was added importance of this mechanism for prostate cancer because lycopene tends to accumulate in prostate tissues.

Elgass S, Cooper A, Chopra M. “Lycopene inhibits angiogenesis in human umbilical vein endothelial cells and rat aortic rings.”  Br J Nutr. 2011 Dec 6:1-9.

Posted on 2012-02-27 WorldHealth.net   Anti-Cancer Mechanism of Tomatoes Revealed
Online Article by The Telegraph March 2012  Cancer ‘slowed by cooked tomatoes’



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